Anti-Varicella—Zoster Virus Bicyclic Nucleosides: Replacement of Furo by Pyrro Base Reduces Antiviral Potency
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چکیده
منابع مشابه
Anti-varicella-zoster virus bicyclic nucleosides: replacement of furo by pyrro base reduces antiviral potency.
We have recently reported the discovery of an entirely new category of potent antiviral agents based on novel deoxynucleoside analogues with unusual fluorescent bicyclic furo base moieties. To probe structure-activity relationships and to seek to optimize the properties of the lead compounds, we prepared pyrro analogues of the furo systems. We herein report the synthesis, characterization and a...
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ژورنال
عنوان ژورنال: Antiviral Chemistry and Chemotherapy
سال: 2000
ISSN: 2040-2066,2040-2066
DOI: 10.1177/095632020001100505